Bulk Custom Proteins

Custom Protein & Enzyme Expression

High‑purity proteins tailored to your workflow.
Reliable supply for drug discovery, biomanufacturing & R&D studies.

Scalable

µg to gram scale production

QC-Verified

Activity-tested, reproducible results

ISO/GMP Principles

ISO9001/GMP principles followed

Service Overview

Bulk Custom Proteins

Whether you’re searching for bespoke enzymes for you life science manufacturing process, creating a new cell-free synthesis process, or developing a new gene therapy modality our custom bulk protein production service delivers precisely what your project requires.

We produce high-purity recombinant proteins in a variety of expression systems, including E. coli (please could you italicise E. coli or under line it, also further down under multiple expression systems), yeast, and insect cells, and offer bespoke options such as mutations, fusion tags, and optimised buffer conditions.

All proteins are rigorously tested and quality-controlled to ensure suitability for demanding applications, including in biomanufacturing, X-ray crystallography, biochemical assays, and biophysical characterisation.

Both RUO and higher specification materials are available, and we’re able to supply in large quantities or higher concentrations, depending on your study or manufacturing needs.

Trusted Expertise

About Inspiralis

We specialise in the production of DNA-modifying enzymes and offer a growing range of molecular biology reagents to clients across biotech, pharmaceutical, and CRO and CDMO sectors.

Based on the Norwich Research Park, we combine scientific rigour with responsive customer service, tailoring our products to meet the exacting standards of research and development teams around the world.

With decades of experience supplying both academic and industrial customers, we are known for our work with topoisomerases, ligases, and helicases – enzymes integral to drug discovery workflows, structural biology studies, and mechanistic research.

Why Choose Inspiralis?

The Benefits of Choosing Inspiralis

  • Highly flexible to meet diverse project scopes and technical requirements.
  • Exceptionally agile, enabling rapid turnaround and responsive support.
  • 15+ years of experience as experts in DNA and DNA-modifying enzymes.

  • Quality-driven across every stage, from expression to final QC.

  • Consistently reliable production with reproducible results across all batches.

  • AI-powered enzyme engineering coming soon for smarter design solutions.

Alternative Supplier

  • Often limited to standard catalogue offerings with minimal customisation.

  • Slower response times and less adaptable to changing project needs.

  • Broader focus, with less depth in specialised enzyme systems.

  • Quality may vary with fewer controls in place for custom projects.

  • Reproducibility can be a challenge across batches or suppliers.

  • Limited innovation; slower to adopt emerging technologies like AI.

We selected Inspiralis as our supplier because their product was far and away the highest quality, and excellent value. However, beyond their product quality and consistency, we found Inspiralis to be an incredibly communicative and collaborative partner – going above and beyond providing us data to enable our own process development, sourcing a boutique shipping company to ensure our high-dollar-value shipment arrived safely and still frozen, or working at all hours to produce an extra large, last-minute, and highly urgent request. I would very happily work with Inspiralis again in the future.
Manager of Operations & Planning, A Gene Therapy Coompany, USA
The KDNA we purchased from Inspiralis is much better than the one from Inspiralis’s competitors. We have noticed a significant improvement in stability and reproducibility of results when we started to use KDNA from Inspiralis. We have also performed super resolution microscopy and AFM on the KDNA and the integrity and purity of the samples are by far the best.
Davide Michieletto, Royal Society University Research Fellow
What truly sets Inspiralis apart is their deep understanding of the research process and the needs of researchers. They are not merely suppliers but true research partners. Their team is consistently communicative, collaborative, and proactive, often going above and beyond to ensure our projects run smoothly.
I am thoroughly satisfied with their partnership and I will not hesitate to work with Inspiralis again in the future. Their speed, quality, and dedication to understanding our research needs have made all the difference. We have published more than 20 papers on bacterial gyrase and human Topoisomerase, and Inspiralis’ expertise was an important factor in our success, highlighting their commitment to advancing scientific knowledge.
Prof. Dr. Janez Ilaš, Professor of Medicinal Chemistry - University of Ljubljana, Faculty of Pharmacy

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